CN
Diethyl 1,1-cyclobutanedicarboxylate
| Identification | Chinese Name: | 1,1-环丁基二甲酸二乙酯 | ||
| English Name: | Diethyl 1,1-cyclobutanedicarboxylate | |||
| CAS No.: | 3779-29-1 | Abbreviation / Alias | CBDE | |
| Structural Formula: | ||||
| Molecular Formula: | C10H16O4 | Molecular Weight | 200.23 | |
| HS Code: | 2916209090 | UN No.: | / | |
| Physical and Chemical Properties | Appearance and Properties: | Colorless transparent liquid | ||
| Main Applications: | An important pharmaceutical intermediate, used to synthesize carboplatin and related compounds. | |||
| Assay | ≥99.00% | Moisture: | ≤0.2% | |
| Relative Density (water = 1): | 1.05 | Flash Point (°C): | 89℃ | |
| Melting Point: | / | Boiling Point: | 104-105°C | |
| Hazard Class: | / | 、 | 、 | |
| Packaging and Transport | Packing Group: | / | Packaging: | 25 kg/plastic drum; smaller packs available |
| Storage and Transport Notes: | Store sealed, dry and protected from light, at room temperature. | |||
| Status | Commercial production | |||
Diethyl 1,1-cyclobutanedicarboxylate Specs
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<td colspan="3" height="19" style="height: 19px; width: 452px;" x:str="">Item</td>
<td colspan="2" style="width: 342px;" x:str="">Specification</td>
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<td colspan="3" height="19" style="height: 19px; width: 452px;" x:str="">Appearance</td>
<td colspan="2" style="width: 342px;" x:str="">Colorless to pale yellow transparent liquid</td>
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<td colspan="3" height="19" style="height: 19px; width: 452px;" x:str="">Assay</td>
<td colspan="2" style="width: 342px;" x:num="0.98">≥99.00%</td>
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<td colspan="3" height="19" style="height: 19px; width: 452px;" x:str="">Unknown single impurity</td>
<td colspan="2" style="width: 342px;" x:str="">≤0.5% </td>
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<td colspan="3" height="19" style="height: 19px; width: 452px;" x:str="">Moisture</td>
<td colspan="2" style="width: 342px;" x:str="">≤0.2% </td>
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Product Introduction
<p>Diethyl 1,1-cyclobutanedicarboxylate (CAS 3779-29-1), molecular weight 200.23, is a colorless transparent liquid. It is insoluble in water and readily soluble in organic solvents. It is an important pharmaceutical intermediate, made by cyclizing diethyl malonate with 1,3-dibromopropane. Hydrolysis gives 1,1-cyclobutanedicarboxylic acid, used mainly to synthesize the antitumor drug carboplatin. It is also a building block for compounds with a cyclobutane skeleton. Industrial material is generally ≥98% by GC. Store sealed in a cool place. It irritates the skin, eyes and respiratory tract.</p>